Reactive species
Human,Mouse,Rat
Immunogen
A synthetic phosphorylated peptide around S65 of human Ubiquitin
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
UBC; S27A; CEP80; UBA80; HEL112; UBCEP1; UBCEP80; L40; CEP52; RPL40; HUBCEP52; HELS-50; HMG20; Phospho-Ubiquitin-Ser65
Background
Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in
targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the
maintenance of chromatin structure, the regulation of gene expression, and the stress
response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin
chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion
protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C
terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived
from this gene are present in the genome
