Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of
human AK1
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
HTL-S-58j; AK1
Background
This gene encodes an adenylate kinase enzyme involved in energy metabolism and
homeostasis of cellular adenine nucleotide ratios in different intracellular compartments.
This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations
in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic
disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results
in multiple transcript variants encoding different isoforms. This gene shares readthrough
transcripts with the upstream ST6GALNAC6 gene
