Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of
human Na+/K+-ATPase
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
CMT2DD; HOMGSMR2; Na+/K+-ATPase
Background
The protein encoded by this gene belongs to the family of P-type cation transport ATPases,
and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein
responsible for establishing and maintaining the electrochemical gradients of Na and K ions
across the plasma membrane. These gradients are essential for osmoregulation, for sodiumcoupled transport of a variety of organic and inorganic molecules, and for electrical
excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic
subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -
ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple
transcript variants encoding different isoforms have been found for this gene.
