Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 45-124 of human
HE4/WFDC2 (Q14508)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
HE4; WAP5; EDDM4; dJ461P17.6; HE4/WFDC2
Background
This gene encodes a protein that is a member of the WFDC domain family. The WFDC
domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the
core of the protein, and functions as a protease inhibitor in many family members. This gene
is expressed in pulmonary epithelial cells, and was also found to be expressed in some
ovarian cancers. The encoded protein is a small secretory protein, which may be involved in
sperm maturation.