Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human
Glutaminase (GLS) (O94925).
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
GAC; GAM; KGA; GLS1; AAD20; DEE71; GDPAG; CASGID; EIEE71; Glutaminase (GLS)
Function
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an
phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate
and ammonia. This protein is primarily expressed in the brain and kidney plays an essential
role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate
and maintaining acid-base balance in the kidney. Alternate splicing results in multiple
transcript variants
