Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SETD7
(Q8WTS6)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
KMT7; SET7; SET9; SET7/9; SETD7
Function
Enables histone-lysine N-methyltransferase activity and p53 binding activity. Involved in
peptidyl-lysine dimethylation and peptidyl-lysine monomethylation. Acts upstream of or
within cellular response to DNA damage stimulus and heterochromatin organization. Located
in chromosome and nucleolus.