Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 42-179 of
human FZD4 (NP_036325.2)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; CD344; FZD4S; FZD4
Background
This gene is a member of the frizzled gene family. Members of this family encode seventransmembrane domain proteins that are receptors for the Wingless type MMTV integration
site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin
canonical signaling pathway. This protein may play a role as a positive regulator of the
Wingless type MMTV integration site signaling pathway. A transcript variant retaining
intronic sequence and encoding a shorter isoform has been described, however, its
expression is not supported by other experimental evidence
