Reactive species
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from human protein.AA range:350-449
Specificity
This antibody detects endogenous levels of Clusterin.
Constitute
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Dilution rate
WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Purification process
Protein G
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Other name
CLU ;
APOJ ;
CLI ;
KUB1 ;
AAG4 ;
Clusterin ;
Aging-associated gene 4 protein ;
Apolipoprotein J ;
Apo-J ;
Complement cytolysis inhibitor ;
CLI ;
Complement-associated protein SP-40 ;
40 ;
Ku70-binding protein 1 ;
NA1/NA2 ;
Testosterone-repressed prostate m
Background
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011],
Function
Function:Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis).,similarity:Belongs to the clusterin family.,subunit:Antiparallel disulfide-linked heterodimer. Interacts with APOA1, CLUAP1 AND PON1.,
