Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 52-275 of
human TERF1 (NP_059523.2).
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
TRF; PIN2; TRF1; TRBF1; t-TRF1; hTRF1-AS; TERF1
Background
This gene encodes a telomere specific protein which is a component of the telomere
nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and
functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual
chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization
domain near its N-terminus and an acidic N-terminus. Multiple transcripts of this gene are
alternatively spliced products.
