Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of
human NGLY1 (NP_060767.2)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
CDDG; PNG1; CDG1V; PNG-1; PNGase; NGLY1
Background
This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-Dglucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide
containing an aspartate residue. The encoded enzyme may play a role in the proteasomemediated degradation of misfolded glycoproteins. Multiple transcript variants encoding
different isoforms have been found for this gene.
