Reactive species
Human,Mouse,Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 545-644 of human
Cytokeratin 1 (KRT1) (P04264)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
K1; CK1; EHK; AEI2; EHK1; EPPK; KRT1A; NEPPK; Cytokeratin 1 (KRT1)
Background
The protein encoded by this gene is a member of the keratin gene family. The type II
cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic
keratin chains coexpressed during differentiation of simple and stratified epithelial tissues.
This type II cytokeratin is specifically expressed in the spinous and granular layers of the
epidermis with family member KRT10 and mutations in these genes have been associated
with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in
a region of chromosome 12q12-q13.
