Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of
human GART (NP_000810.1)
Dilution rate
WB 1:500-2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
AIRS; GARS; PAIS; PGFT; PRGS; GARTF; GART
Background
The protein encoded by this gene is a trifunctional polypeptide. It has
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase,
phosphoribosylaminoimidazole synthetase activity which is required for de novo purine
biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this
gene results in two transcript variants encoding different isoforms.