Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of
human MGLL
Dilution rate
WB 1:1000- 1:5000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
MGL; HUK5; MAGL; HU-K5; MGLL
Background
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the
conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays
a critical role in several physiological processes including pain and nociperception through
hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play
a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants
encoding multiple isoforms have been observed for this gene.
