Background
This gene encodes a member of an antimicrobial peptide family, characterized by a highly
conserved N-terminal signal peptide containing a cathelin domain and a structurally variable
cationic antimicrobial peptide, which is produced by extracellular proteolysis from the Cterminus. The protein plays an important role in innate immunity defense against viruses. In
addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions
in cell chemotaxis, immune mediator induction, and inflammatory response regulation.
