Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of
human MAT1A (NP_000420.1).
Dilution rate
WB 1:500 - 1:2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
MAT; SAMS; MATA1; SAMS1; MAT1A
Background
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of
ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is
subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for
most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a
homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene.
Mutations in this gene are associated with methionine adenosyltransferase deficiency
