Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of
human AKR1C1 (NP_001344.2)
Dilution rate
WB 1:1000- 1:3000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD;
AKR1C1
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more
than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes
and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors.
The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes
the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene
shares high sequence identity with three other gene members and is clustered with those
three genes at chromosome 10p15-p14.
