Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 401-589 of
human CTIP1/BCL11A (Q9H165).
Dilution rate
WB 1:500 - 1:1000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
EVI9; CTIP1; DILOS; ZNF856; HBFQTL5; SMARCM1; 1A
Background
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9
protein. The corresponding mouse gene is a common site of retroviral integration in myeloid
leukemia, and may function as a leukemia disease gene, in part, through its interaction with
BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly
involved in lymphoma pathogenesis since translocations associated with B-cell malignancies
also deregulates its expression. Multiple transcript variants encoding several different
isoforms have been found for this gene.
