Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 24-92 of
human GNRH1 (NP_001076580.1).
Dilution rate
WB 1:500 - 1:1000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
GRH; GNRH; LHRH; LNRH; GNRH1
Background
This gene encodes a preproprotein that is proteolytically processed to generate a peptide
that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides.
Alternative splicing results in multiple transcript variants, at least one of which is secreted
and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1.
Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism.
