Reactive species
Human,Mouse,Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 151-400 of
human WWP2 (NP_001257383.1).
Dilution rate
WB 1:500 - 1:2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
AIP2; WWp2-like; WWP2
Background
This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role
in protein ubiquitination. The encoded protein contains four WW domains and may play a
role in multiple processes including chondrogenesis and the regulation of oncogenic
signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for
this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.
