Reactive species
Human,Mouse,Rat (predicted:Pig,Cow,Chicken)
Dilution rate
WB (1:500-2000)
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Background
This gene is a member of a group of genes whose transcript levels are increased following
stressful growth arrest conditions and treatment with DNA-damaging agents. The protein
encoded by this gene responds to environmental stresses by mediating activation of the
p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this
gene is mediated by both p53 dependent and independent mechanisms.
