Reactive species
Human;Mouse;Rat
Protein name
Rho GTPase-activating protein 12
Immunogen
Synthesized peptide derived from ARHGAP12 . at AA range: 310-390
Specificity
ARHGAP12 Monoclonal Antibody detects endogenous levels of ARHGAP12 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
ARHGAP12; Rho GTPase-activating protein 12; Rho-type GTPase-activating protein 12
Background
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
Function
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 WW domains.,
