Reactive species
Human;Mouse;Rat
Protein name
Vesicle-fusing ATPase
Immunogen
Synthesized peptide derived from NSF . at AA range: 110-190
Specificity
NSF Monoclonal Antibody detects endogenous levels of NSF protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NSF; Vesicle-fusing ATPase; N-ethylmaleimide-sensitive fusion protein; NEM-sensitive fusion protein; Vesicular-fusion protein NSF
Background
catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.,similarity:Belongs to the AAA ATPase family.,subunit:Homohexamer. Interacts with GABARAP and GABARAPL2.,
Function
catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.,similarity:Belongs to the AAA ATPase family.,subunit:Homohexamer. Interacts with GABARAP and GABARAPL2.,
