Reactive species
Human,Mouse,Rat
Protein name
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (Protein H105e3)
Immunogen
Synthesized peptide derived from human NSDHL
Specificity
This antibody detects endogenous levels of NSDHL at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Plays also a role in the regulation of the endocytic trafficking of EGFR (By similarity).
