Reactive species
Human,Mouse,Rat
Applications
WB、IHC、IF、ELISA
Gene Name
HSP90AA1/HSP90AB1
Protein name
Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta
Immunogen
The antiserum was produced against synthesized peptide derived from human HSP90A/B around the non-acetylation site of Lys292/284. AA range:251-300
Specificity
HSP 90 Polyclonal Antibody detects endogenous levels of HSP 90 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Other name
HSP90AA1 ;
HSP90A ;
HSPC1 ;
HSPCA ;
Heat shock protein HSP 90-alpha ;
Heat shock 86 kDa ;
HSP 86 ;
HSP86 ;
Renal carcinoma antigen NY-REN-38 ;
HSP90AB1 ;
HSP90B ;
HSPC2 ;
HSPCB ;
Heat shock protein HSP 90-beta ;
HSP 90 ;
Heat shock 84 kDa ;
HSP 84 ;
HSP84
Background
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
Function
Caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,Function:Molecular chaperone.,Function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,
