Reactive species
Human;Rat;Mouse
Applications
WB;IHC;IF;ELISA
Antibody type
Monoclonal antibodies
Immunogen
Synthetic Peptide of Phospho-Stat3 (Y705) at AA range of 640-720
Specificity
Phospho-Stat3 (Y705) protein detects endogenous levels of STAT3
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 500-2000 IHC 1:50-300. IF 1:50-200
Purification process
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein
