Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Probable G-protein coupled receptor 139
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR139. AA range:181-230
Specificity
GPR139 Polyclonal Antibody detects endogenous levels of GPR139 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
GPR139; GPRG1; PGR3; Probable G-protein coupled receptor 139; G(q)-coupled orphan receptor GPRg1; G-protein-coupled receptor PGR3
Background
This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Function
function:Orphan receptor. Seems to act through a G(q/11)-mediated pathway.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues.,
