Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
C-C chemokine receptor-like 2
Immunogen
The antiserum was produced against synthesized peptide derived from human CCRL2. AA range:141-190
Specificity
CCRL2 Polyclonal Antibody detects endogenous levels of CCRL2 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
CCRL2; CCR11; CCR6; CKRX; CRAM; HCR; C-C chemokine receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; Putative MCP-1 chemokine receptor
Background
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008],
Function
function:Receptor for CCL2, CCL5, CCL7 and CCL8.,tissue specificity:Expressed abundantly in immunal tissues such as spleen, fetal liver, lymph node and bone marrow. Strong expression also in lung and heart.,
