Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
C-C chemokine receptor type 11
Immunogen
The antiserum was produced against synthesized peptide derived from human CCRL1. AA range:291-340
Specificity
CCRL1 Polyclonal Antibody detects endogenous levels of CCRL1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
CCRL1; CCBP2; CCR11; VSHK1; C-C chemokine receptor type 11; C-C CKR-11; CC-CKR-11; CCR-11; CC chemokine receptor-like 1; CCRL1; CCX CKR
Background
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013],
Function
function:Receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Predominantly expressed in heart. Lower expression in lung, pancreas, spleen, colon, skeletal muscle and small intestine.,
