Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Proto-oncogene Mas
Immunogen
Synthetic Peptide of Mas1
Specificity
The antibody detects endogenous Mas1 protein.
Constitute
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB: 1:2000-5000 IHC: 1:200-500. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
MAS1; MAS; Proto-oncogene Mas
Background
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012],
Function
caution:Was originally (PubMed:3419518) thought to be a receptor for angiotensin II.,disease:The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,
