Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Neurotensin/neuromedin N
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human NTS. AA range:121-170
Specificity
Neurotensin Polyclonal Antibody detects endogenous levels of Neurotensin protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NTS; Neurotensin/neuromedin N
Background
This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014],
Function
function:Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.,online information:Neurotensin entry,similarity:Belongs to the neurotensin family.,subcellular location:Packaged within secretory vesicles.,
