Reactive species
Human;Mouse;Rat
Applications
IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Slit homolog 3 protein
Immunogen
Synthesized peptide derived from the Internal region of human Slit3.
Specificity
Slit3 Polyclonal Antibody detects endogenous levels of Slit3 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
SLIT3; KIAA0814; MEGF5; SLIL2; Slit homolog 3 protein; Slit-3; Multiple epidermal growth factor-like domains protein 5; Multiple EGF-like domains protein 5
Background
The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],
Function
function:May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.,sequence caution:Intron retention.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 23 LRR (leucine-rich) repeats.,similarity:Contains 9 EGF-like domains.,tissue specificity:Predominantly expressed in thyroid.,
