Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Protein name
Neuromedin-U receptor 1
Immunogen
The antiserum was produced against synthesized peptide derived from human NMUR1. AA range:1-50
Specificity
NMUR1 Polyclonal Antibody detects endogenous levels of NMUR1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NMUR1; GPR66; Neuromedin-U receptor 1; NMU-R1; G-protein coupled receptor 66; G-protein coupled receptor FM-3
Background
caution:It is uncertain whether Met-1 or Met-24 is the initiator.,function:Receptor for the neuromedin-U and neuromedin-S neuropeptides.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.,
Function
caution:It is uncertain whether Met-1 or Met-24 is the initiator.,function:Receptor for the neuromedin-U and neuromedin-S neuropeptides.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.,
