Reactive species
Human;Mouse
Applications
IHC;IF;ELISA
Antibody type
Polyclonal Antibody
Protein name
Neuron navigator 1
Immunogen
Synthesized peptide derived from Neuron Navigator 1 . at AA range: 510-590
Specificity
Neuron Navigator 1 Polyclonal Antibody detects endogenous levels of Neuron Navigator 1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NAV1; KIAA1151; KIAA1213; POMFIL3; STEERIN1; Neuron navigator 1; Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1
Background
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],
Function
developmental stage:Expressed in fetal brain and heart.,function:May be involved in neuronal migration.,similarity:Belongs to the Nav/unc-53 family.,subcellular location:Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones.,subunit:Interacts with tubulin.,tissue specificity:Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.,
