Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
DnaJ homolog subfamily C member 5
Immunogen
The antiserum was produced against synthesized peptide derived from human DNAJC5. AA range:131-180
Specificity
CSP Polyclonal Antibody detects endogenous levels of CSP protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
DNAJC5; CSP; DnaJ homolog subfamily C member 5; Cysteine string protein; CSP
Background
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010],
Function
function:May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.,PTM:Fatty acylated. Heavily palmitoylated in the cysteine string motif.,similarity:Contains 1 J domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.,
