Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
TSSK6 SSTK FKSG82
Immunogen
Synthesized peptide derived from human TSSK6
Specificity
This antibody detects endogenous levels of TSSK6 at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, and 0.61% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Other name
Testis-specific serine/threonine-protein kinase 6 (TSK-6) (TSSK-6) (Testis-specific kinase 6) (EC 2.7.11.1) (Cancer/testis antigen 72) (CT72) (Serine/threonine-protein kinase SSTK) (Small serine/threonine kinase)
Background
This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A. These interactions appear to be required for TSSK6 kinase activity.,tissue specificity:Highly expressed in testis. Expressed at lower levels in human colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.,
