Reactive species
Human; Mouse;Rat
Applications
WB;ELISA;IHC
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human STXB2 AA range: 392-442
Specificity
This antibody detects endogenous levels of STXB2 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013],
Function
function:Involved in the protein trafficking from the Golgi apparatus to the plasma membrane.,similarity:Belongs to the STXBP/unc-18/SEC1 family.,subunit:Binds syntaxins 1A, 2, 3 but not 4.,tissue specificity:Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.,
