Reactive species
Human;Rat;Mouse;
Applications
WB;ELISA;IHC
Antibody type
Polyclonal Antibody
Gene Name
LRRN2 GAC1 LRRN5 UNQ256/PRO293
Immunogen
Synthesized peptide derived from human LRRN2 AA range: 296-346
Specificity
This antibody detects endogenous levels of LRRN2 at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,tissue specificity:Overamplified in malignant gliomas.,
