Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human ARH40 AA range: 1261-1311
Specificity
This antibody detects endogenous levels of ARH40 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014],
Function
function:May act as a guanine nucleotide exchange factor (GEF).,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,subcellular location:Concentrated in the perinuclear region.,tissue specificity:Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level).,
