Antibody type
Polyclonal Antibody
Gene Name
AMELY AMGL AMGY
Immunogen
Synthesized peptide derived from human AMELY.AA range 17-57
Specificity
This antibody detects endogenous levels of AMELY at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008],
Function
developmental stage:Transiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.,function:Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.,miscellaneous:This isoform is encoded on the Y chromosome.,similarity:Belongs to the amelogenin family.,
