Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
TBC1D7 HSPC239 TBC7
Immunogen
Synthesized peptide derived from human TBCD7 AA range: 85-135
Specificity
This antibody detects endogenous levels of TBCD7 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the TBC-domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1-TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus and downstream LOC100130357. [provided by RefSeq, Jan 2016],
Function
function:May act as a GTPase-activating protein for Rab family protein(s) .,similarity:Contains 1 Rab-GAP TBC domain.,