Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human CISY AA range: 272-322
Specificity
This antibody detects endogenous levels of CISY at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.,miscellaneous:Citrate synthase is found in nearly all cells capable of oxidative metabolism.,online information:Citrate synthase entry,pathway:Carbohydrate metabolism; tricarboxylic acid cycle.,sequence caution:Intron retention.,similarity:Belongs to the citrate synthase family.,subunit:Homodimer.,