Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
CMYA5 C5orf10 DTNBP2 SPRYD2 TRIM76
Immunogen
Synthesized peptide derived from human CMYA5 AA range: 3866-3916
Specificity
This antibody detects endogenous levels of CMYA5 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
IHC-p 1：50-200. IF 1:50-200
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
domain:Amphipathic helix regions act as an anchoring domain for PKA, and appear to be responsible of the interaction between myospryn and PRKAR2A.,induction:Down-regulated in muscle cell lines derived from patients with Duchenne muscular dystrophy (DMD).,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Translated as Trp.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 2 fibronectin type-III domains.,subcellular location:Found predominantly at the periphery of the nucleus but also throughout the cell. Localized at the Z-line costamere connection level of the sarcolemma and in lysosomes.,subunit:Interacts with ACTN2, DTNBP1/dysbindin and PRKAR2A (By similarity). Interacts with DES.,tissue specificity:Expressed in skeletal muscle; at a strong level and in heart.,
