Reactive species
Human;Rat;Mouse;
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human CLLU1 AA range: 23-73
Specificity
This antibody detects endogenous levels of CLLU1 at Human
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is overexpressed in chronic lymphocytic leukemia (CLL) and serves as a good prognostic marker for the disease. Methylation of certain genes, including this one, have been associated with CLL. This gene is protein-coding in humans and non-protein coding in other primates. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015],
Function
disease:High CLLU1 expression in patients with CLL is associated with poor clinical outcome.,miscellaneous:Tridimensional modeling predicts that it may interact with the IL-4 receptor.,tissue specificity:Specifically expressed in chronic lymphocytic leukemia (CLL) cells from patients without immunoglobulin heavy-chain hypermutations.,
