Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human ASCC3 AA range: 2053-2103
Specificity
This antibody detects endogenous levels of ASCC3 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Function
function:Enhances NF-kappa-B, SRF and AP1 transactivation.,similarity:Belongs to the helicase family.,similarity:Contains 2 helicase ATP-binding domains.,similarity:Contains 2 helicase C-terminal domains.,similarity:Contains 3 SEC63 domains.,subunit:Part of TRIP4 complex, that contains ASCC1, ASCC2 and ASCC3.,tissue specificity:Ubiquitous.,
