Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
FOXD1 FKHL8 FREAC4
Immunogen
Synthesized peptide derived from human FOXD1 AA range: 82-132
Specificity
This antibody detects endogenous levels of FOXD1 at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Studies of the orthologous mouse protein indicate that it functions in kidney development by promoting nephron progenitor differentiation, and it also functions in the development of the retina and optic chiasm. It may also regulate inflammatory reactions and prevent autoimmunity. [provided by RefSeq, Apr 2014],
Function
function:Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly.,similarity:Contains 1 fork-head DNA-binding domain.,