Reactive species
Human; Mouse;Rat
Antibody type
Polyclonal Antibody
Immunogen
Synthesized peptide derived from human FDFT AA range: 11-61
Specificity
This antibody detects endogenous levels of FDFT at Human/Mouse/Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008],
Function
catalytic activity:2 farnesyl diphosphate = diphosphate + presqualene diphosphate.,catalytic activity:Presqualene diphosphate + NAD(P)H = squalene + diphosphate + NAD(P)(+).,cofactor:Magnesium.,pathway:Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl-PP: step 1/3.,similarity:Belongs to the phytoene/squalene synthetase family.,subunit:Monomer.,
