Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
CETN1 CEN1 CETN
Immunogen
Synthesized peptide derived from human CETN1 AA range: 96-146
Specificity
This antibody detects endogenous levels of CETN1 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jan 2015],
Function
function:Plays a fundamental role in microtubule-organizing center structure and function.,miscellaneous:Binds two moles of calcium per mole of protein.,similarity:Belongs to the centrin family.,similarity:Contains 4 EF-hand domains.,subcellular location:Centrosome of interphase and mitotic cells.,subunit:Monomer.,