Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
BAZ1A ACF1 WCRF180 HSPC317
Immunogen
Synthesized peptide derived from human BAZ1A AA range: 736-786
Specificity
This antibody detects endogenous levels of BAZ1A at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010],
Function
function:May play a role in transcriptional regulation. May be involved in the formation or maintenance of heterochromatin playing a critical role in developmental control.,miscellaneous:Stimulated by double-stranded DNA and nucleosomal DNA.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 WAC domain.,subcellular location:May target the CHRAC complex to heterochromatin.,subunit:Together with CHRAC1, POLE3 and SMARCA5 proteins, it forms the ISWI chromatin-remodeling complex, CHRAC.,tissue specificity:Highly expressed in testis and at low or undetectable levels in other tissues analyzed.,
