Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
RIPK4 ANKRD3 DIK
Immunogen
Synthesized peptide derived from human RIPK4 AA range: 280-330
Specificity
This antibody detects endogenous levels of RIPK4 at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1：500-2000
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Plays a role in NF-kappa B activation.,PTM:May be phosphorylated by MAP3K2 and MAP3K3.,PTM:Proteolytically cleaved by during Fas-induced apoptosis. Cleavage at Asp-388 and Asp-426.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 10 ANK repeats.,subunit:Interacts with PRKCB (By similarity). Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.,
