Reactive species
Human; Mouse
Antibody type
Polyclonal Antibody
Gene Name
LRRC3B LRP15 UNQ195/PRO221
Immunogen
Synthesized peptide derived from human LRC3B AA range: 115-165
Specificity
This antibody detects endogenous levels of LRC3B at Human/Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015],
Function
similarity:Belongs to the LRRC3 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,
